Hospital Readmission Rates in Patients With Neuromyelitis Optica Spectrum Disorder

Abstract Background: Neuromyelitis optica spectrum disorder (NMOSD) is an aggressive central nervous system astrocytopathy often resulting in rapid neurologic decline. Patients have recurrent flares that require immunomodulatory therapy for relapse prevention. These patients are usually hospitalized and may need rehospitalization after Hospital readmission rates important indicators can be used to gauge health care quality direct implications on hospital compensation. This study aims identify high-risk characteristics of with NMOSD predict readmissions. Methods: The 2017 Nationwide Readmissions Database was searched admissions the United States. All within 30 days discharge from index hospitalization were included. Results: 30-day all-cause rate 11.9% (95% confidence interval, 10.6%–13.3%). aged 65 74 years had higher odds readmission; those private insurance decreased odds. Sex did not affect readmission. Several comorbidities, such as respiratory failure, peripheral vascular disease, neurocognitive disorders, blindness, predictive Plasma exchange increased readmission, whereas intravenous immunoglobulin infusions, chemotherapies monoclonal antibodies, Conclusions: most common etiologies neurologic, infectious, respiratory. Treatment targeted toward these result reduced overall thereby decreasing disease burden.